About   Help   FAQ
Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
11.5 DPC

26 matching records from 26 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Trp63  transformation related protein 63   (Synonyms: deltaNp63, KET protein, p51/p63, p63, p73L, TAp63, Trp53rp1)
Results  Reference
1J:119657 Cheng W, Jacobs WB, Zhang JJ, Moro A, Park JH, Kushida M, Qiu W, Mills AA, Kim PC, DeltaNp63 plays an anti-apoptotic role in ventral bladder development. Development. 2006 Dec;133(23):4783-92
1J:221100 Choi KS, Lee C, Maatouk DM, Harfe BD, Bmp2, Bmp4 and Bmp7 are co-required in the mouse AER for normal digit patterning but not limb outgrowth. PLoS One. 2012;7(5):e37826
1J:153098 Goss AM, Tian Y, Tsukiyama T, Cohen ED, Zhou D, Lu MM, Yamaguchi TP, Morrisey EE, Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev Cell. 2009 Aug;17(2):290-8
1*J:136080 Guttormsen J, Koster MI, Stevens JR, Roop DR, Williams T, Winger QA, Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol. 2008 May 1;317(1):187-95
1J:272569 Hou Z, Wu Q, Sun X, Chen H, Li Y, Zhang Y, Mori M, Yang Y, Que J, Jiang M, Wnt/Fgf crosstalk is required for the specification of basal cells in the mouse trachea. Development. 2019 Feb 11;146(3):dev171496
1J:252735 Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J, Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. 2017 Oct 26;550(7677):529-533
1J:167544 Jurado S, Smyth I, van Denderen B, Tenis N, Hammet A, Hewitt K, Ng JL, McNees CJ, Kozlov SV, Oka H, Kobayashi M, Conlan LA, Cole TJ, Yamamoto K, Taniguchi Y, Takeda S, Lavin MF, Heierhorst J, Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis. PLoS Genet. 2010;6(10):e1001170
1J:146225 Kameda Y, Ito M, Nishimaki T, Gotoh N, FRS2alpha is required for the separation, migration, and survival of pharyngeal-endoderm derived organs including thyroid, ultimobranchial body, parathyroid, and thymus. Dev Dyn. 2009 Mar;238(3):503-13
1J:316647 Kameda Y, Saitoh T, Nemoto N, Katoh T, Iseki S, Fujimura T, Hes1 is required for the development of pharyngeal organs and survival of neural crest-derived mesenchymal cells in pharyngeal arches. Cell Tissue Res. 2013 Jul;353(1):9-25
1J:292005 Kim E, Jiang M, Huang H, Zhang Y, Tjota N, Gao X, Robert J, Gilmore N, Gan L, Que J, Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation. Dev Cell. 2019 Dec 16;51(6):675-683.e4
1*J:100707 Kurita T, Cunha GR, Robboy SJ, Mills AA, Medina RT, Differential expression of p63 isoforms in female reproductive organs. Mech Dev. 2005 Sep;122(9):1043-55
1J:234990 Li S, Morley M, Lu M, Zhou S, Stewart K, French CA, Tucker HO, Fisher SE, Morrisey EE, Foxp transcription factors suppress a non-pulmonary gene expression program to permit proper lung development. Dev Biol. 2016 Aug 15;416(2):338-46
1J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82
1J:258790 Lungova V, Verheyden JM, Sun X, Thibeault SL, beta-Catenin signaling is essential for mammalian larynx recanalization and the establishment of vocal fold progenitor cells. Development. 2018 Feb 16;145(4):dev157677
1J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68
1J:291294 McAuley E, Moline D, VanOpstall C, Lamperis S, Brown R, Vander Griend DJ, Sox2 Expression Marks Castration-Resistant Progenitor Cells in the Adult Murine Prostate. Stem Cells. 2019 May;37(5):690-700
1J:94647 Nakamuta N, Kobayashi S, Expression of p63 in the mouse primordial germ cells. J Vet Med Sci. 2004 Nov;66(11):1365-70
1*J:197339 Pignon JC, Grisanzio C, Geng Y, Song J, Shivdasani RA, Signoretti S, p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8105-10
1J:122531 Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan BL, Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development. 2007 Jul;134(13):2521-31
1J:210664 Restelli M, Lopardo T, Lo Iacono N, Garaffo G, Conte D, Rustighi A, Napoli M, Del Sal G, Perez-Morga D, Costanzo A, Merlo GR, Guerrini L, DLX5, FGF8 and the Pin1 isomerase control DeltaNp63alpha protein stability during limb development: a regulatory loop at the basis of the SHFM and EEC congenital malformations. Hum Mol Genet. 2014 Jul 15;23(14):3830-42
1J:166768 Rodriguez P, Da Silva S, Oxburgh L, Wang F, Hogan BL, Que J, BMP signaling in the development of the mouse esophagus and forestomach. Development. 2010 Dec;137(24):4171-6
1J:149319 Romano RA, Ortt K, Birkaya B, Smalley K, Sinha S, An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate. PLoS One. 2009;4(5):e5623
1J:298302 Ru J, Guo D, Fan J, Zhang J, Ju R, Ouyang H, Wei L, Liu Y, Liu C, Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis. Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):6
1J:301269 Sankoda N, Tanabe W, Tanaka A, Shibata H, Woltjen K, Chiba T, Haga H, Sakai Y, Mandai M, Yamamoto T, Yamada Y, Uemoto S, Kawaguchi Y, Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021 Jan 25;12(1):560
1J:334564 Tanaka K, Matsumaru D, Suzuki K, Yamada G, Miyagawa S, The role of p63 in embryonic external genitalia outgrowth in mice. Dev Growth Differ. 2023 Feb;65(2):132-140
1J:139045 Thomason HA, Dixon MJ, Dixon J, Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling. Dev Biol. 2008 Sep 1;321(1):273-82

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory